The mechanisms of action of ivermectin against SARS-CoV-2—an extensive review
et al., The Journal of Antibiotics, doi:10.1038/s41429-021-00491-6 (Review)
, The mechanisms of action of ivermectin against SARS-CoV-2—an extensive review, The Journal of Antibiotics, doi:10.1038/s41429-021-00491-6 (Review)
Extensive review of 20 mechanisms of action of ivermectin for SARS-CoV-2.
Zaidi et al., 21 Dec 2021, peer-reviewed, 2 authors.
Abstract: The Journal of Antibiotics (2022) 75:60–71
https://doi.org/10.1038/s41429-021-00491-6
REVIEW ARTICLE
The mechanisms of action of ivermectin against SARS-CoV-2—an
extensive review
Asiya Kamber Zaidi
1
●
Puya Dehgani-Mobaraki
1
Received: 20 October 2021 / Revised: 9 November 2021 / Accepted: 10 November 2021 / Published online: 21 December 2021
© The Author(s), under exclusive licence to the Japan Antibiotics Research Association 2021
1234567890();,:
1234567890();,:
Abstract
Considering the urgency of the ongoing COVID-19 pandemic, detection of new mutant strains and potential re-emergence of
novel coronaviruses, repurposing of drugs such as ivermectin could be worthy of attention. This review article aims to
discuss the probable mechanisms of action of ivermectin against SARS-CoV-2 by summarizing the available literature over
the years. A schematic of the key cellular and biomolecular interactions between ivermectin, host cell, and SARS-CoV-2 in
COVID-19 pathogenesis and prevention of complications has been proposed.
Loading..
Please send us corrections, updates, or comments. Vaccines and
treatments are complementary. All practical, effective, and safe means should
be used based on risk/benefit analysis. No treatment, vaccine, or intervention
is 100% available and effective for all current and future variants. We do not
provide medical advice. Before taking any medication, consult a qualified
physician who can provide personalized advice and details of risks and
benefits based on your medical history and situation. FLCCC and WCH
provide treatment protocols.