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The mechanisms of action of ivermectin against SARS-CoV-2—an extensive review
Zaidi et al., The Journal of Antibiotics, doi:10.1038/s41429-021-00491-6 (Review)
Zaidi et al., The mechanisms of action of ivermectin against SARS-CoV-2—an extensive review, The Journal of Antibiotics, doi:10.1038/s41429-021-00491-6 (Review)
Dec 2021   Source   PDF  
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Extensive review of 20 mechanisms of action of ivermectin for SARS-CoV-2.
Zaidi et al., 21 Dec 2021, peer-reviewed, 2 authors.
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Abstract: The Journal of Antibiotics (2022) 75:60–71 https://doi.org/10.1038/s41429-021-00491-6 REVIEW ARTICLE The mechanisms of action of ivermectin against SARS-CoV-2—an extensive review Asiya Kamber Zaidi 1 ● Puya Dehgani-Mobaraki 1 Received: 20 October 2021 / Revised: 9 November 2021 / Accepted: 10 November 2021 / Published online: 21 December 2021 © The Author(s), under exclusive licence to the Japan Antibiotics Research Association 2021 1234567890();,: 1234567890();,: Abstract Considering the urgency of the ongoing COVID-19 pandemic, detection of new mutant strains and potential re-emergence of novel coronaviruses, repurposing of drugs such as ivermectin could be worthy of attention. This review article aims to discuss the probable mechanisms of action of ivermectin against SARS-CoV-2 by summarizing the available literature over the years. A schematic of the key cellular and biomolecular interactions between ivermectin, host cell, and SARS-CoV-2 in COVID-19 pathogenesis and prevention of complications has been proposed.
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