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All Studies   Meta Analysis   Recent: 
Does ivermectin have a place in the treatment of mild Covid-19?
Schwartz, E., New Microbes and New Infections, doi:10.1016/j.nmni.2022.100989 (Review)
27 May 2022    Source   PDF   Share   Tweet
Discussion of ivermectin research compared to paxlovid and molnupiravir. Author includes a meta analysis of low-risk-of-bias studies showing significantly lower hospitalization for outpatient treatment with ivermectin. This efficacy is seen even though treatment was relatively late on average, and even though the Together Trial has been included.
The Together Trial highlights the limitations of risk-of-bias analysis as opposed to more detailed analysis of actual bias. While the Together Trial may theoretically have a low risk of bias at a superficial level when ignoring the conflicts of interest, in practice the bias is very large due to known impossible data, blinding failure, randomization failure, and many protocol failures, in addition to extremely large conflicts of interest [c19ivermectin.com].
Update: [sciencedirect.com]
Schwartz et al., 27 May 2022, peer-reviewed, 1 author.
Contact: elischwa@tauex.tau.ac.il.
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