White paper on Ivermectin as a potential therapy for COVID-19
Panel review of ivermectin reporting that "ivermectin in the dose of 12mg BD alone or in combination with other therapy for 5–7 days may be considered as safe therapeutic option for mild moderate or severe cases of Covid-19 infection. It is cost effective especially when the other drugs are very costly & not easily available".
Vora et al., 31 Jul 2020, peer-reviewed, 4 authors.
Abstract: i n d i a n j o u r n a l o f t u b e r c u l o s i s 6 7 ( 2 0 2 0 ) 4 4 8 e4 5 1
Available online at www.sciencedirect.com
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journal homepage: http://www.journals.elsevier.com/
indian-journal-of-tuberculosis/
Letter to the Editor
White paper on Ivermectin as a potential therapy
for COVID-19
abstract
Keywords:
A group of senior doctors with vast clinical experience met on 19th July’20 under the aegis
Antiviral
of Academy of Advanced Medical Education. The panel looked at Ivermectin, one of the old
Coronavirus
molecule and evaluated it's use in COVID 19 (Novel Coronavirus Disease 2019) manage-
Infection
ment. After critical panel discussion, all the attending doctors came to a conclusion that
Pandemic
Ivermectin can be a potential molecule for prophylaxis and treatment of people infected
PCR
with Coronavirus, owing to its anti-viral properties coupled with effective cost, availability
SARS-CoV-2
and good tolerability and safety.
© 2020 Tuberculosis Association of India. Published by Elsevier B.V. All rights reserved.
1.
Executive summary
SARS-CoV-2, a small 100 nm virus has emerged as an elusive
foe, threatening mankind. Currently India is placed 3rd in
terms of number of reported cases which warrants newer
therapeutic treatment options that are widely available,
affordable, effective and safe.
There are newer drugs on the horizon which have been
recommended though with very limited experience & devoid
of enough data about safety and efficacy.1 These newer options are neither easily available nor affordable.
We have revisited some of the old molecules & have found
Ivermectin, originally introduced as an anthelmintic to be an
effective, safe and affordable therapeutic option in Indian
settings for prevention and treatment of COVID-19.2
Recent research has shown that Ivermectin possesses
strong anti-viral properties.3 It has potential to convert RTPCR negative quickly.4 It can be used across the severity of
COVID-19 especially in early viremic phase.5 It can be combined with other molecules of interest, like Hydroxychloroquine, azithromycin, doxycycline.6 Ivermectin is
affordable, easily available, and safe without any major side
effects.5
This white paper is an attempt to propose Ivermectin, a
strong antiviral drug as a therapeutic option in the prevention
and treatment of mild, moderate and severe cases of COVID-19.
A group of senior doctors with vast experience in the
management of COVID-19 got together on 19th July’20 under
the leadership of Prof Dr V. K. Arora, Prof. Dr D. Behera, Prof.
Dr Suryakant Tripathy, Dr. MohanKumar Thekkinkattil, Dr.
Agam Vora, Dr. Vasant Nagvekar, Lt Gen (Rtd) Dr. B.N.B.M
Prasad, Dr. K.S. Satish, Dr. V.K.Singh, Dr. Mangesh Tiwaskar,
Dr. Parthiv Mehta, Dr. P. Sarat Singh, Dr. Narayana Pradeep,
Dr. Rahul Mayekar and Dr. Bhupesh Dewan, under the auspices of Academy of Advanced Medical Education. Many of the
attending doctors shared their personal experience of using
Ivermectin successfully with very good results in their patients. The group, at the end of the discussion, proposed the
following consensus statement:
“Ivermectin in the dose of 12 mg BD alone or in combination with other therapy for 5 to 7 days may be considered
as safe therapeutic option for mild moderate or severe
cases of Covid-19 infection. It is cost effective especially
when the other drugs are very costly & not easily
available”.
However, the group strongly feels the urgent need for a
well-designed..
Please send us corrections, updates, or comments. Vaccines and
treatments are complementary. All practical, effective, and safe means should
be used based on risk/benefit analysis. No treatment, vaccine, or intervention
is 100% available and effective for all current and future variants. We do not
provide medical advice. Before taking any medication, consult a qualified
physician who can provide personalized advice and details of risks and
benefits based on your medical history and situation.
FLCCC and
WCH
provide treatment protocols.
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