Ivermectin as a SARS-CoV-2 Pre-Exposure Prophylaxis Method in Healthcare Workers: A Propensity Score-Matched Retrospective Cohort Study

DOI record: { "DOI": "10.7759/cureus.17455", "ISSN": [ "2168-8184" ], "URL": "http://dx.doi.org/10.7759/cureus.17455", "author": [ { "affiliation": [], "family": "Morgenstern", "given": "Jose", "sequence": "first" }, { "affiliation": [], "family": "Redondo", "given": "Jose N", "sequence": "additional" }, { "affiliation": [], "family": "Olavarria", "given": "Alvaro", "sequence": "additional" }, { "affiliation": [], "family": "Rondon", "given": "Isis", "sequence": "additional" }, { "affiliation": [], "family": "Roca", "given": "Santiago", "sequence": "additional" }, { "affiliation": [], "family": "De Leon", "given": "Albida", "sequence": "additional" }, { "affiliation": [], "family": "Canela", "given": "Juan", "sequence": "additional" }, { "affiliation": [], "family": "Tavares", "given": "Johnny", "sequence": "additional" }, { "affiliation": [], "family": "Minaya", "given": "Miguelina", "sequence": "additional" }, { "affiliation": [], "family": "Lopez", "given": "Oscar", "sequence": "additional" }, { "affiliation": [], "family": "Castillo", "given": "Ana", "sequence": "additional" }, { "affiliation": [], "family": "Placido", "given": "Ana", "sequence": "additional" }, { "affiliation": [], "family": "Cruz", "given": "Rafael", "sequence": "additional" }, { "affiliation": [], "family": "Merette", "given": "Yudelka", "sequence": "additional" }, { "affiliation": [], "family": "Toribio", "given": "Marlenin", "sequence": "additional" }, { "affiliation": [], "family": "Francisco", "given": "Juan", "sequence": "additional" } ], "container-title": "Cureus", "content-domain": { "crossmark-restriction": false, "domain": [] }, "created": { "date-parts": [ [ 2021, 8, 26 ] ], "date-time": "2021-08-26T11:30:21Z", "timestamp": 1629977421000 }, "deposited": { "date-parts": [ [ 2024, 2, 9 ] ], "date-time": "2024-02-09T19:34:50Z", "timestamp": 1707507290000 }, "indexed": { "date-parts": [ [ 2024, 3, 28 ] ], "date-time": "2024-03-28T16:35:33Z", "timestamp": 1711643733509 }, "is-referenced-by-count": 6, "issued": { "date-parts": [ [ 2021, 8, 26 ] ] }, "language": "en", "link": [ { "URL": "https://www.cureus.com/articles/63131-ivermectin-as-a-sars-cov-2-pre-exposure-prophylaxis-method-in-healthcare-workers-a-propensity-score-matched-retrospective-cohort-study", "content-type": "unspecified", "content-version": "vor", "intended-application": "similarity-checking" } ], "member": "297", "original-title": [], "prefix": "10.7759", "published": { "date-parts": [ [ 2021, 8, 26 ] ] }, "published-print": { "date-parts": [ [ 2021, 8, 26 ] ] }, "publisher": "Springer Science and Business Media LLC", "reference": [ { "DOI": "10.1016/j.antiviral.2020.104787", "article-title": "The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro", "author": "Caly L", "doi-asserted-by": "publisher", "journal-title": "Antiviral Res", "key": "ref1", "unstructured": "Caly L, Druce JD, Catton MG, Jans DA, Wagstaff KM. The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro. Antiviral Res. 2020, 178:104787. 10.1016/j.antiviral.2020.104787", "volume": "178", "year": "2020" }, { "DOI": "10.1101/2021.05.31.21258081", "article-title": "Favorable outcome on viral load and culture viability using Ivermectin in early treatment of non-hospitalized patients with mild COVID-19 - a double-blind, randomized placebo-controlled trial [PREPRINT]", "author": "Biber A", "doi-asserted-by": "publisher", "journal-title": "medRxiv", "key": "ref2", "unstructured": "Biber A, Mandelboim M, Harmelin G, et al.. 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