An Updated Systematic Review and Meta-Analysis of Mortality, Need for ICU admission, Use of Mechanical Ventilation, Adverse effects and other Clinical Outcomes of Ivermectin Treatment in COVID-19 Patients
MBBS Smruti Karale, MBBS, MPH Vikas Bansal, MBBS Janaki Makadia, Muhammad Tayyeb, Hira Khan, Shree Spandana Ghanta, MBBS Romil Singh, MD Aysun Tekin, Abhishek Bhurwal, MD Hemant Mutneja, MBB Ishita Mehra, MBBS, MBA Rahul Kashyap
doi:10.1101/2021.04.30.21256415
Highlights What We Already Know about This Topic
1. COVID-19 is an ongoing global pandemic, for which Ivermectin has been tried on a therapeutic and prophylactic basis.
2. Results from several clinical trials and observational studies suggest that Ivermectin may improve survival and clinical outcomes with a good safety profile when compared with other treatments; however, the current evidence is limited. .
What This Article Tells Us That Is New 1. This systematic review and meta-analysis provide a summary of the latest literature on the efficacy and safety of Ivermectin use for COVID-19.
2. Based on our analysis of the latest evidence, we found that Ivermectin's benefit in reducing mortality cannot be concluded with confidence . However, as an adjuvant
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