COVID-19 In-Hospital Mortality Rate is Reduced by Prophylactic Use of Ivermectin: Findings From a City-Wide, Prospective Observational Study Using Propensity Score Matching (PSM)
Kerr et al.,
COVID-19 In-Hospital Mortality Rate is Reduced by Prophylactic Use of Ivermectin: Findings From a City-Wide,..,
Research Gate, doi:10.13140/RG.2.2.26793.52327 (Preprint)
PSM retrospective 378 hospitalized patients in Brazil, showing lower mortality for patients that were on ivermectin prophylaxis before admission (not taking into account the lower risk of being hospitalized shown in the related larger study).
This study is excluded in meta
analysis:
patients in this study are a subset of those in a larger study; not taking into account the lower risk of hospitalization shown in the related larger study.
risk of death, 45.0% lower, RR 0.55, p = 0.046, treatment 12 of 52 (23.1%), control 22 of 52 (42.3%), NNT 5.2, adjusted per study, propensity score matching, multivariable.
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Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
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Kerr et al., 31 Dec 2021, retrospective, propensity score matching, Brazil, preprint, 9 authors, study period July 2020 - December 2020, dosage 200μg/kg days 1, 2, 16, 17, 0.2mg/kg/day for 2 days every 15 days.
Abstract: See discussions, stats, and author profiles for this publication at: https://www.researchgate.net/publication/357333781
COVID-19 In-Hospital Mortality Rate is Reduced by Prophylactic Use of
Ivermectin: Findings From a City-Wide, Prospective Observational Study
Using Propensity Score Matching (PSM)
Preprint · December 2021
DOI: 10.13140/RG.2.2.26793.52327
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São Paulo State University
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Some of the authors of this publication are also working on these related projects:
ESTUDO DA VARIABILIDADE GENÉTICA DO PERFIL DE ACIDOS GRAXOS DA CARNE DE BOVINOS DA RAÇA NELORE TERMINADOS EM CONFINAMENTO View project
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COVID-19 In-Hospital Mortality Rate is Reduced by Prophylactic Use of
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Ivermectin: Findings From a City-Wide, Prospective Observational Study Using
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Propensity Score Matching (PSM)
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Lucy Kerr, MD, ARDMS1, Fernando Baldi, PhD2, Raysildo Barbosa Lôbo, PhD3,
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Washington Luiz Olivato Assagra4, Fernando Carlos Proença5, Jennifer A. Hibberd, DDS,
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DPD, MRCDC6, Juan J Chamie-Quintero7, Pierre Kory, MD, MPA8, Flavio A. Cadegiani,
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MD, MSc, PhD8,9*
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Instituto Kerr de Ensino e Pesquisa, São Paulo, Brazil
Department of Animal Sciences, State University of São Paulo, São Paulo, Brazil
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Department of Genetics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão
Preto, Brazil.
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Centro Técnico de Avaliação Genômica C.T.A.G, Ribeirão Preto, Brazil
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Itajaí City Hall, Itajaí, Brazil
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University of Toronto, Toronto, Canada
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Data Analysis, Universidad EAFIT, Cambridge, USA
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Front-Line Covid-19 Critical Care Alliance (FLCCC), USA
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Corpometria Institute, Brasilia, Brazil
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*Corresponding author:
Flávio A. Cadegiani, MD, MSc, PhD
Corpometria Institute
SGAS 915 Centro Clínico Advance, Rooms 260/262/264, Brasília, DF, Brazil
f.cadegiani@gmail.com, flavio.cadegiani@unifesp.br, flavio@flccc.net
+55 61 981.395.395
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Key-words: COVID-19, SARS-CoV-2, ivermectin, prophylaxis, prevention,
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coronavirus
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Acromyums: COPD = Chronic Obstructive Pulmonary Disease; CVD = cardiovascular
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disease; MI = Myocardial infarction; T2D = Type 2 Diabetes
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Abstract
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vaccines, a medical-based citywide governmental program offered ivermectin
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prophylaxis for COVID-19 (city of Itajaí, state of Santa Catarina, Southern Brazi). The
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aim of the present study was to evaluate the impact of prophylactic ivermectin use in in-
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hospital COVID-19 mortality rate.
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Materials and methods: We analyzed data from hospitalized COVID-19 patients of a
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major COVID-19 reference hospital during a city-wide program of ivermectin
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prophylaxis for COVID-19 (Hospital Marieta Konder Bornhausen, Itajaí, Santa Catarina,
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Brazil), between July and December 2020. We..
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