Analysis of COVID-19 cases vs. widespread prophylactic use of ivermectin for parasitic infections showing significantly lower incidence of COVID-19 cases.
This is the 22nd of 99 COVID-19 controlled studies
for ivermectin, which collectively show efficacy with p<0.0000000001 (1 in 2 sextillion)
. 46 studies are RCTs
, which show efficacy with p=0.00000014
This study is excluded in the after exclusion results of meta
not a typical trial, analysis of African countries that used or did not use ivermectin prophylaxis for parasitic infections.
risk of case, 78.0% lower, RR 0.22, p < 0.02, African countries, PCTI vs. no PCT, relative cases per capita.
risk of case, 80.0% lower, RR 0.20, p < 0.001, worldwide, PCTI vs. no PCT, relative cases per capita.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Hellwig et al., 28 Nov 2020, retrospective, ecological study, multiple countries, peer-reviewed, 2 authors, dosage 200μg/kg, dose varied, typically 150-200μg/kg.
A COVID-19 prophylaxis? Lower incidence associated with prophylactic administration of ivermectin
International Journal of Antimicrobial Agents, doi:10.1016/j.ijantimicag.2020.106248
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Supplementary materials Supplementary material associated with this article can be found, in the online version, at doi:10.1016/j.ijantimicag.2020. 106248 .
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