Effects of a Single Dose of Ivermectin on Viral and Clinical Outcomes in Asymptomatic SARS-CoV-2 Infected Subjects: A Pilot Clinical Trial in Lebanon
et al., Viruses,
Effects of a Single Dose of Ivermectin on Viral and Clinical Outcomes in Asymptomatic SARS-CoV-2 Infected..
, Viruses, doi:10.3390/v13060989 (results 1/16)
This study was retracted.
Samaha et al., 16 Jan 2021, peer-reviewed, 16 authors.
Effects of a Single Dose of Ivermectin on Viral and Clinical
Outcomes in Asymptomatic SARS-CoV-2 Infected Subjects: A
Pilot Clinical Trial in Lebanon
Ali A. Samaha 1,2,3,4,† , Hussein Mouawia 1,† , Mirna Fawaz 2 , Hamad Hassan 1,5 , Ali Salami 6 , Ali Al Bazzal 1 ,
Hamid Bou Saab 7 , Mohamed Al-Wakeel 8 , Ahmad Alsaabi 9 , Mohamad Chouman 1 , Mahmoud Al Moussawi 10 ,
Hassan Ayoub 4 , Ali Raad 1 , Ola Hajjeh 1 , Ali H. Eid 11,12, * and Houssam Raad 1, *
Citation: Samaha, A.A.; Mouawia,
H.; Fawaz, M.; Hassan, H.; Salami, A.;
Bazzal, A.A.; Saab, H.B.; Al-Wakeel,
M.; Alsaabi, A.; Chouman, M.; et al.
Effects of a Single Dose of Ivermectin
Faculty of Public Health, Lebanese University, Beirut, Lebanon; firstname.lastname@example.org (A.A.S.);
email@example.com (H.M.); firstname.lastname@example.org (H.H.); email@example.com (A.A.B.);
firstname.lastname@example.org (M.C.); email@example.com (A.R.); firstname.lastname@example.org (O.H.)
Nursing Department, Faculty of Health Sciences, Beirut Arab University, Beirut, Mazraa 1105, Lebanon;
Department of Biomedical Sciences, Lebanese International University, Beirut, Mazraa 1105, Lebanon
Department of Cardiology, Rayak University Hospital, Bekaa 1801, Lebanon; email@example.com
Ministry of Health, Beirut, Lebanon
Department of Mathematics, Faculty of Sciences, Lebanese University, Nabatieh 1700, Lebanon;
Faculty of Sciences, Lebanese University, Zahle 1801, Lebanon; firstname.lastname@example.org
Karbala Health Directory, Baghdad 10081, Iraq; email@example.com
Department of Biology, Lille University, 59160 Lille, France; firstname.lastname@example.org
Faculty of Nursing Sciences, Islamic University of Lebanon, Baalbek 1800, Lebanon; dr.Mmouss@yahoo.com
Department of Basic Medical Sciences, College of Medicine, QU Health, Qatar University, Doha, Qatar
Biomedical and Pharmaceutical Unit, QU Health, Qatar University, Doha, Qatar
Correspondence: email@example.com (A.H.E.); firstname.lastname@example.org (H.R.); Tel.: +974-4403-7893 (A.H.E.)
These authors contributed equally to this work.
on Viral and Clinical Outcomes in
Asymptomatic SARS-CoV-2 Infected
Subjects: A Pilot Clinical Trial in
Lebanon. Viruses 2021, 13, 989.
Academic Editors: Kenneth
Lundstrom and Alaa A. A. Aljabali
Received: 19 March 2021
Accepted: 9 May 2021
Published: 26 May 2021
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Abstract: Objective: This study was designed to determine the efficacy of ivermectin, an FDAapproved drug, in producing clinical benefits and decreasing the viral load of SARS-CoV-2 among
asymptomatic subjects that tested positive for this virus in Lebanon. Methods: A randomized
controlled trial was conducted in 100 asymptomatic Lebanese subjects that have tested positive for
SARS-CoV2. Fifty patients received standard preventive treatment, mainly supplements, and the
experimental group received a single dose (according to body weight) of ivermectin, in addition
to the same supplements the control group received. Results: There was no significant difference
(p = 0.06) between Ct-values of the two groups before the regimen was started (day zero), indicating
that subjects in both groups had similar viral loads. At 72 h after the regimen started, the increase
in Ct-values was dramatically higher in..
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