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0 0.5 1 1.5 2+ Mortality 100% Improvement Relative Risk Hospitalization 100% Mortality (b) 97% Hospitalization (b) 99% c19ivm.org Tyson et al. Ivermectin for COVID-19 EARLY TREATMENT Favors ivermectin Favors control
Low Rates of Hospitalization and Death in 4,376 COVID-19 Patients Given Early Ambulatory Medical and Supportive Care. A Case Series and Observational Study.
Tyson et al., Preprint (Preprint)
13 Jan 2022    Source   PDF   Share   Tweet
Retrospective 4,376 patients with mild/moderate COVID-19 in the USA treated with multiple medications including HCQ/ivermectin, favipiravir, vitamin C, D, quercetin, zinc, mAbs, budesonide, dexamethasone, prednisone, and colchicine (exact treatments specific to each patient), showing significantly lower hospitalization and mortality compared to the surrounding community.
risk of death, 99.8% lower, RR 0.002, p < 0.001, treatment 0 of 3,962 (0.0%), control 471 of 20,921 (2.3%), NNT 44, relative risk is not 0 because of continuity correction due to zero events (with reciprocal of the contrasting arm), All AVUC mild patients vs. Imperial County (corrected).
risk of hospitalization, 99.8% lower, RR 0.002, p < 0.001, treatment 2 of 3,962 (0.1%), control 4,343 of 20,921 (20.8%), NNT 4.8, All AVUC mild patients vs. Imperial County (corrected).
risk of death, 97.0% lower, RR 0.03, p < 0.001, treatment 3 of 4,375 (0.1%), control 471 of 20,921 (2.3%), NNT 46, All AVUC patients vs. Imperial County (corrected).
risk of hospitalization, 99.0% lower, RR 0.010, p < 0.001, treatment 9 of 4,375 (0.2%), control 4,343 of 20,921 (20.8%), NNT 4.9, All AVUC patients vs. Imperial County (corrected).
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Tyson et al., 13 Jan 2022, retrospective, USA, preprint, 13 authors.
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