Abstract: Journal Pre-proof Ivermectin administration is associated with lower gastrointestinal complications and greater ventilator-free days in ventilated patients with COVID-19: A propensity score analysis Kentaro Shimizu, Haruhiko Hirata, Daijiro Kabata, Natsuko Tokuhira, Moe Koide, Akiko Ueda, Jotaro Tachino, Ayumi Shintani, Akinori Uchiyama, Yuji Fujino, Hiroshi Ogura PII: S1341-321X(21)00360-3 DOI: https://doi.org/10.1016/j.jiac.2021.12.024 Reference: JIC 1790 To appear in: Journal of Infection and Chemotherapy Received Date: 18 September 2021 Revised Date: 11 November 2021 Accepted Date: 26 December 2021 Please cite this article as: Shimizu K, Hirata H, Kabata D, Tokuhira N, Koide M, Ueda A, Tachino J, Shintani A, Uchiyama A, Fujino Y, Ogura H, Ivermectin administration is associated with lower gastrointestinal complications and greater ventilator-free days in ventilated patients with COVID-19: A propensity score analysis, Journal of Infection and Chemotherapy (2022), doi: https://doi.org/10.1016/ j.jiac.2021.12.024. This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. © 2021 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved. (Title Page) 1) Title Ivermectin administration is associated with lower gastrointestinal complications and greater ventilator-free days in ventilated patients with COVID-19: A propensity score analysis oo f 2) Author names and affiliations re -p r (Authors) Kentaro Shimizu1, shimiken@hp-emerg.med.osaka-u.ac.jp lP Haruhiko Hirata2, charhirata@imed3.med.osaka-u.ac.jp ur na Daijiro Kabata3, kabata.daijiro@med.osaka-cu.ac.jp Natsuko Tokuhira4, tokuhira@hosp.med.osaka-u.ac.jp Jo Moe Koide4, koide@hosp.med.osaka-u.ac.jp Akiko Ueda5, aueda@hp-lab.med.osaka-u.ac.jp Jotaro Tachino1, jotarotachino@hp-emerg.med.osaka-u.ac.jp Ayumi Shintani, ayumi.shintani@gmail.com Akinori Uchiyama4, auchiyama@hp-icu.med.osaka-u.ac.jp Yuji Fujino4, fujino@anes.med.osaka-u.ac.jp Hiroshi Ogura1, ogura@hp-emerg.med.osaka-u.ac.jp (Affiliations) 1 1 Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, Japan 2 Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, Osaka University 2-2 Yamadaoka, Suita 565-0871, Japan 3 oo f Department of Medical Statistics, Osaka City University Graduate School of Medicine, 1-4-3, 4 re -p r Asahimachi, Abeno-ku, Osaka, 545-0051, Japan Intensive Care Unit, Osaka University Hospital, Osaka University, Japan lP 2-15 Yamadaoka, Suita, Osaka 565-0871, Japan 5 ur na Laboratory for Clinical Investigation, Osaka University Hospital, Osaka University, Japan Jo 2-15 Yamadaoka, Suita, Osaka 565-0871, Japan 3) Corresponding author: Kentaro Shimizu, M.D. Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, 2-15 Yamadaoka, Suita-city, Osaka..