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All Studies   Meta Analysis   Recent: 
0 0.5 1 1.5 2+ Viral clearance 87% primary Improvement Relative Risk Viral clearance (b) 58% c19ivm.org Elalfy et al. Ivermectin for COVID-19 EARLY TREATMENT Favors ivermectin Favors control
Effect of a combination of Nitazoxanide, Ribavirin and Ivermectin plus zinc supplement (MANS.NRIZ study) on the clearance of mild COVID-1
Elalfy et al., J. Med. Virol., doi:10.1002/jmv.26880
16 Feb 2021    Source   PDF   Share   Tweet
Non-randomized controlled trial with 62 mild and early moderate patients with home treatment with ivermectin + nitazoxanide + ribavirin + zinc, showing significantly faster viral clearance.
risk of no viral clearance, 86.9% lower, RR 0.13, p < 0.001, treatment 7 of 62 (11.3%), control 44 of 51 (86.3%), NNT 1.3, day 15, primary outcome.
risk of no viral clearance, 58.1% lower, RR 0.42, p < 0.001, treatment 26 of 62 (41.9%), control 51 of 51 (100.0%), NNT 1.7, day 7.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Elalfy et al., 16 Feb 2021, retrospective, Egypt, peer-reviewed, 15 authors, dosage 18mg days 1, 4, 7, 10, 13, <90kg 18mg, 90-120kg 24mg, >120kg 30mg, this trial uses multiple treatments in the treatment arm (combined with nitazoxanide, ribavirin, and zinc) - results of individual treatments may vary.
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