Conv. Plasma
Nigella Sativa

All ivermectin studies
Meta analysis
study COVID-19 treatment researchIvermectinIvermectin (more..)
Melatonin Meta
Metformin Meta
Azvudine Meta
Bromhexine Meta Molnupiravir Meta
Budesonide Meta
Colchicine Meta
Conv. Plasma Meta Nigella Sativa Meta
Curcumin Meta Nitazoxanide Meta
Famotidine Meta Paxlovid Meta
Favipiravir Meta Quercetin Meta
Fluvoxamine Meta Remdesivir Meta
Hydroxychlor.. Meta Thermotherapy Meta
Ivermectin Meta

All Studies   Meta Analysis    Recent:   
0 0.5 1 1.5 2+ Case 91% Improvement Relative Risk Ivermectin for COVID-19  Alam et al.  Prophylaxis Does ivermectin reduce COVID-19 infections? Prospective study of 118 patients in Bangladesh Fewer cases with ivermectin (p<0.000001) Alam et al., European J. Medical and H.., Dec 2020 Favors ivermectin Favors control

Ivermectin as Pre-exposure Prophylaxis for COVID-19 among Healthcare Providers in a Selected Tertiary Hospital in Dhaka – An Observational Study

Alam et al., European Journal of Medical and Health Sciences, doi:10.24018/ejmed.2020.2.6.599
Dec 2020  
  Source   PDF   All   Meta
Ivermectin for COVID-19
4th treatment shown to reduce risk in August 2020
*, now known with p < 0.00000000001 from 100 studies, recognized in 22 countries.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
3,800+ studies for 60+ treatments.
91% reduction in COVID-19 cases with ivermectin prophylaxis. 118 healthcare workers in Bangladesh, 58 receiving ivermectin 12mg monthly, showing RR 0.094, p < 0.0001.
This is the 27th of 100 COVID-19 controlled studies for ivermectin, which collectively show efficacy with p<0.0000000001 (1 in 1 sextillion). 47 studies are RCTs, which show efficacy with p=0.0000002.
risk of case, 90.6% lower, RR 0.09, p < 0.001, treatment 4 of 58 (6.9%), control 44 of 60 (73.3%), NNT 1.5.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Alam et al., 15 Dec 2020, prospective, Bangladesh, peer-reviewed, 13 authors, dosage 12mg monthly.
This PaperIvermectinAll
Ivermectin as Pre-exposure Prophylaxis for COVID-19 among Healthcare Providers in a Selected Tertiary Hospital in Dhaka – An Observational Study
Mohammed Tarek Alam, Rubaiul Murshed, Pauline Francisca Gomes, Zafor Md. Masud, Mainul Sadia Saber, Mainul Alam Chaklader, Fatema Khanam, Monower Hossain, Abdul Basit Ibne Momen Momen, Naz Yasmin, Rafa Faaria Alam, Amrin Sultana, Rishad Choudhury Robin
European Journal of Medical and Health Sciences, doi:10.24018/ejmed.2020.2.6.599
I. BACKGROUND Submerged in the wave of Coronavirus disease 2019 (COVID-19), the world is weeping. Ever since the outbreak was first identified in December 2019 in Wuhan, China the world has not been the same [1] . An ongoing pandemic, the COVID-19 has proved to be the most devastating and unmanageable crisis the world has ever encountered. With the virus proudly lurking around in the atmosphere, millions of lives have already been compromised and many more uncountable innocents are still fighting to survive this war against the invisible rival. The call for an authentic treatment protocol against this virus was made long before
Adedokun, Olarinmoye, Mustapha, Kamorudeen, A close look at the biology of SARS-CoV-2, and the potential influence of weather conditions and seasons on COVID-19 case spread, Infectious Diseases of Poverty
Alam, Murshed, Bhiuyan, Saber, Alam et al., Case Series of 100 COVID-19 Positive Patients Treatedwith Combination of Ivermectin and Doxycycline, Journal of Bangladesh College of Physicians and Surgeons
Azeem, Ashraf, Rasheed, Anjum, Hameed, Evaluation of cytotoxicity and antiviral activity of ivermectin against Newcastle disease virus, Pak J Pharm Sci
Baraka, Mahmoud, Marschke, Geary, Homeida et al., Ivermectin distribution in the plasma and tissues of patients infected with Onchocerca volvulus, Eur J Clin Pharmacol
Caly, Druce, Catton, Jans, Wagstaff, The FDAapproved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro, Antiviral Res
Crump, Ivermectin: enigmatic multifaceted 'wonder' drug continues to surprise and exceed expectations, J Antibiot
Crump, Ōmura, Ivermectin, 'wonder drug' from Japan: the human use perspective, Proceedings of the Japan Academy Series B, Physical and biological sciences
Götz, Magar, Dornfeld, Influenza A viruses escape from MxA restriction at the expense of efficient nuclear vRNP import, Scientific Reports
Hopkins, Treating neglected tropical diseases, Community eye health
Ivermectin, Meyler's Side Effects of Drugs
Kylie, Sivakumaran, Steven, Harrich, David, Ivermectin is a specific inhibitor of importin α/βmediated nuclear import able to inhibit replication of HIV-1 and dengue virus, Biochemical Journal
Lee, Lee, Ivermectin inhibits porcine reproductive and respiratory syndrome virus in cultured porcine alveolar macrophages, Archives of Virology
Lundberg, Pinkham, Baer, Nuclear import and export inhibitors alter capsid protein distribution in mammalian cells and reduce Venezuelan Equine Encephalitis Virus replication, Antiviral Research
Lv, Liu, Wang, Ivermectin inhibits DNA polymerase UL42 of pseudorabies virus entrance into the nucleus and proliferation of the virus in vitro and vivo, Antiviral Research
Mastrangelo, Pezzullo, Burghgraeve, Ivermectin is a potent inhibitor of flavivirus replication specifically targeting NS3 helicase activity: new prospects for an old drug, Journal of Antimicrobial Chemotherapy
Merck, Over 30 Years: The Mectizan Donation Program
Msd, MECTIZAN Donation Program
Muñoz, Ballester, Antonijoan, Safety and pharmacokinetic profile of fixed-dose ivermectin with an innovative 18mg tablet in healthy adult volunteers, PLoS neglected tropical diseases
Nguyen, Burton, Kuklinski, Gray, Foy, Ivermectin for the Control of West Nile Virus Transmission, New Horizons in Translational Medicine
Nguyen, Sakuna, Kinobe, Owens, Ivermectin blocks the nuclear location signal of parvoviruses in crayfish, Cherax quadricarinatus, Aquaculture
Nicholas, Rafael, Powell, A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection, Cell Host & Microbe
Raza, Shahin, Zhai, Ivermectin Inhibits Bovine Herpesvirus 1 DNA Polymerase Nuclear Import and Interferes with Viral Replication, Microorganisms
Satoshi, None
Sharun, Dhama, Patel, Ivermectin, a new candidate therapeutic against SARS-CoV-2/COVID-19, Annals of Clinical Microbiology and Antimicrobials
Tielsch, Beeche, Impact of ivermectin on illness and disability associated with onchocerciasis, Tropical Medicine & International Health
Varghese, Kaukinen, Gläsker, Discovery of berberine, abamectin and ivermectin as antivirals against chikungunya and other alphaviruses, Antiviral Research
Wang, Lv, Wang, Qiu, Yang, Ivermectin treatment inhibits the replication of Porcine circovirus 2 (PCV2) in vitro and mitigates the impact of viral infection in piglets, Virus Research
Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Vaccines and treatments are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment, vaccine, or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
  or use drag and drop