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Repurposing Drugs for Covid-19 by a Developing Country

Valerio Pascua et al., Epidemiology International Journal, doi:10.23880/eij-16000234
May 2022  
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Ivermectin for COVID-19
4th treatment shown to reduce risk in August 2020
*, now known with p < 0.00000000001 from 102 studies, recognized in 22 countries.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
4,000+ studies for 60+ treatments.
Review of a multiphasic multidrug early treatment protocol for COVID-19 in Honduras, showing one death from 415 patients, which was for a patient not receiving early treatment (presenting on the 5th day in need of hospitalization and supplemental oxygen). Treatment included ivermectin, aspirin, colchicine, fluvoxamine, and famotidine.
Study covers ivermectin and fluvoxamine.
Valerio Pascua et al., 20 May 2022, Honduras, peer-reviewed, 31 authors, study period November 2020 - October 2021.
This PaperIvermectinAll
Repurposing Drugs for Covid-19 by a Developing Country
Valerio Pascua, Hernández Ci, Lewis As, Valenzuela Hd, Flores, Alvarenga Lf, Diaz, Chajtur Dg, Pineda E15, Vargas M 16, Caraccioli Gg, Garay, Lara R 15, Deras P 18, Leon V 15, Videa Eo, Stevens Ml, Eberhard D 20, Singh J 21, Sekhon Ak, Sierra Hoffman
Epidemiology International Journal, doi:10.23880/eij-16000234
Background: Early treatment of COVID-19 disease with repurposed drugs has been controversial. Most guidelines in the developed world recommend monoclonal antibodies or Ritonavir/Nirmatrelvir therapies for patients at risk of clinical deterioration, but accessibility to these in developing countries is a big challenge. The primary purpose of this study is to
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