Structures and functions of coronavirus replication–transcription complexes and their relevance for SARS-CoV-2 drug design
Brandon Malone, Nadya Urakova, Eric J Snijder, Elizabeth A Campbell
Nature Reviews Molecular Cell Biology, doi:10.1038/s41580-021-00432-z
genome that has mRNA polarity and, when released from viral particles, can be used directly by host ribosomes to produce viral proteins.
Author contributions The authors contributed equally to all aspects of the article.
Competing interests E.A.C has received funding from Gilead Sciences to fund research on remdesivir's incorporation into the RNAdependent RNA polymerase. The other authors declare no competing interests.
Peer review information Nature Reviews Molecular Cell Biology thanks Hauke Hillen, Kenneth Johnson and Yi Shi for their contribution to the peer review of this work.
Publisher's note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
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