COVID-19: Post-exposure prophylaxis with ivermectin in contacts. At Homes, Places of Work, Nursing Homes, Prisons, and Others
Chang et al.,
COVID-19: Post-exposure prophylaxis with ivermectin in contacts. At Homes, Places of Work, Nursing Homes,..,
ResearchGate, doi:10.13140/RG.2.2.34561.48483/2 (Preprint) (Theory)
Proposed PEP protocol based on ivermectin.
Chang et al., 31 Jul 2020, preprint, 2 authors.
Abstract: See discussions, stats, and author profiles for this publication at: https://www.researchgate.net/publication/344781515
COVID-19: POST-EXPOSURE PROPHYLAXIS WITH IVERMECTIN IN
CONTACTS.
Preprint · July 2020
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Gustavo Aguirre Chang
Aurora Natividad Trujillo Figueredo
National University of San Marcos
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COVID-19: POST-EXPOSURE PROPHYLAXIS WITH IVERMECTIN IN
CONTACTS. At Homes, Places of Work, Nursing Homes, Prisons, and Others.
Aguirre-Chang, Gustavo and Trujillo, Aurora. ResearchGate. July 30, 2020.
English translation by Madeline Oh
Doi: http://dx.doi.org/10.13140/RG.2.2.34561.48483/3
SUMMARY
Post-Exposure Prophylaxis (PEP) is aimed at preventing the development of infection and
disease after exposure to an infectious agent. PEP is indicated by the WHO, PAHO, the United
States HHS and other widely recognized organizations for HIV infection, as well as for other
infectious diseases such as Hepatitis B and C, Tuberculosis and Scabies.
In the case of COVID-19, PEP is indicated for Contacts of people with a diagnosis of SARS
CoV-2 infection.
The identification of the Contacts of the infected person is carried out mainly in his or her Place
of Residence and Work. If applicable, it is also carried out in School, modes of Transportation
as well as other places where the infected may have stayed. PEP is also recommended in the
case of Contact with persons suspected of having COVID-19.
The Place of Residence may be a place where many people live, such as Nursing Homes,
Prisons, Long-Term Residential Centers, Hospitals, among others. In these places, it is often
justifiable to carry out large-scale PEP, especially if there are several people already sick on
site.
Based on local experience and existing publications, a general PEP Scheme consisting of a
dose of 0.2 mg per kilo of weight for 2 days is proposed. A third dose (3 days) is indicated in
male Contacts between the ages of 45 and 70. And 4 doses is given for men older than 70,
and in the person(s) who assume(n) the role of “Caregiver”.
The inclusion of Acetylsalicylic Acid (ASA) or Aspirin in the PEP Scheme is recommended in
for men over 45 years of age and in “Persons with Increased Risk” of developing severe illness.
Recommended dose is 1 tablet of 100 mg after lunch for 6 to 10 days.
Contacts should remain under observation in case they begin to show characteristic symptoms
of COVID-19, in which case they should move to therapeutic doses of Ivermectin. Special care
must be taken in elderly people who are bedridden or with reduced mobility, in whom health
checks must be more frequent and comprehensive.
Keywords: COVID-19, Prophylaxis, Post-Exposure, Ivermectin, Contacts.
TYPES OF PROPHYLAXIS
Prophylaxis is a measures applied or used to prevent an infection or disease from developing
(1,2). Prophylaxis is applied to people who do not have the infection but who are at risk of
contracting it and take drugs against the infectious agent to prevent infection and disease.
The condition to give Prophylaxis for an infection is that there is..
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