Abstract: See discussions, stats, and author profiles for this publication at: https://www.researchgate.net/publication/344781515 COVID-19: POST-EXPOSURE PROPHYLAXIS WITH IVERMECTIN IN CONTACTS. Preprint · July 2020 CITATIONS READS 0 11,904 2 authors: Gustavo Aguirre Chang Aurora Natividad Trujillo Figueredo National University of San Marcos SIGESA 118 PUBLICATIONS 82 CITATIONS 107 PUBLICATIONS 23 CITATIONS SEE PROFILE Some of the authors of this publication are also working on these related projects: COVID 19 View project Fibromyalgia Syndrome is of Intervertebral Disc Origin View project All content following this page was uploaded by Gustavo Aguirre Chang on 25 March 2021. The user has requested enhancement of the SEE PROFILE COVID-19: POST-EXPOSURE PROPHYLAXIS WITH IVERMECTIN IN CONTACTS. At Homes, Places of Work, Nursing Homes, Prisons, and Others. Aguirre-Chang, Gustavo and Trujillo, Aurora. ResearchGate. July 30, 2020. English translation by Madeline Oh Doi: http://dx.doi.org/10.13140/RG.2.2.34561.48483/3 SUMMARY Post-Exposure Prophylaxis (PEP) is aimed at preventing the development of infection and disease after exposure to an infectious agent. PEP is indicated by the WHO, PAHO, the United States HHS and other widely recognized organizations for HIV infection, as well as for other infectious diseases such as Hepatitis B and C, Tuberculosis and Scabies. In the case of COVID-19, PEP is indicated for Contacts of people with a diagnosis of SARS CoV-2 infection. The identification of the Contacts of the infected person is carried out mainly in his or her Place of Residence and Work. If applicable, it is also carried out in School, modes of Transportation as well as other places where the infected may have stayed. PEP is also recommended in the case of Contact with persons suspected of having COVID-19. The Place of Residence may be a place where many people live, such as Nursing Homes, Prisons, Long-Term Residential Centers, Hospitals, among others. In these places, it is often justifiable to carry out large-scale PEP, especially if there are several people already sick on site. Based on local experience and existing publications, a general PEP Scheme consisting of a dose of 0.2 mg per kilo of weight for 2 days is proposed. A third dose (3 days) is indicated in male Contacts between the ages of 45 and 70. And 4 doses is given for men older than 70, and in the person(s) who assume(n) the role of “Caregiver”. The inclusion of Acetylsalicylic Acid (ASA) or Aspirin in the PEP Scheme is recommended in for men over 45 years of age and in “Persons with Increased Risk” of developing severe illness. Recommended dose is 1 tablet of 100 mg after lunch for 6 to 10 days. Contacts should remain under observation in case they begin to show characteristic symptoms of COVID-19, in which case they should move to therapeutic doses of Ivermectin. Special care must be taken in elderly people who are bedridden or with reduced mobility, in whom health checks must be more frequent and comprehensive. Keywords: COVID-19, Prophylaxis, Post-Exposure, Ivermectin, Contacts. TYPES OF PROPHYLAXIS Prophylaxis is a measures applied or used to prevent an infection or disease from developing (1,2). Prophylaxis is applied to people who do not have the infection but who are at risk of contracting it and take drugs against the infectious agent to prevent infection and disease. The condition to give Prophylaxis for an infection is that there is..